Kalpana M. Merchant: search on Z-Library

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1

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stéphane, Singleton, Andrew, Olanow, C Warren, Merchant, Kalpana M, Bezard, Erwan, Petsko, Gregory A, Meis

Journal:

The Lancet Neurology

Year:

2015

Language:

english

File:

PDF, 904 KB

english, 2015

2

Characterization of dopaminergic influence on striatal-nigral neurotensin systems

Anita Aguado Letter, Lisa A. Matsuda, Kalpana M. Merchant, James W. Gibb, Glen R. Hanson

Journal:

Year:

1987

Language:

english

File:

PDF, 327 KB

english, 1987

3

Blunting of the neurotensin mRNA response to haloperidol in the striatum of aging rats: possible relationship to decline in dopamine D2 receptor expression

Dorcas J. Dobie, Kalpana M. Merchant, Mark W. Hamblin, Govind T. Vatassery, Maurice W. Dysken, Daniel M. Dorsa

Journal:

Year:

1993

Language:

english

File:

PDF, 2.07 MB

english, 1993

4

Clozapine and haloperidol block the induction of behavioral sensitization to amphetamine and associated genomic responses in rats

Zhi-hong Meng, Dawna L. Feldpaush, Kalpana M. Merchant

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 1.54 MB

english, 1998

5

Animal and Translational Models for CNS Drug Discovery || Animal Models of Parkinson's Disease to Aid Drug Discovery and Development

Merchant, Kalpana M.

Year:

2008

Language:

english

File:

PDF, 472 KB

english, 2008

6

Higher Urine bis(Monoacylglycerol)Phosphate Levels in LRRK2 G2019S Mutation Carriers: Implications for Therapeutic Development

Alcalay, Roy N., Hsieh, Frank, Tengstrand, Elizabeth, Padmanabhan, Shalini, Baptista, Marco, Kehoe, Caitlin, Narayan, Sushma, Boehme, Amelia K., Merchant, Kalpana

Journal:

Movement Disorders

Year:

2019

File:

PDF, 512 KB

2019

7

P3-444

Frasier, Mark, DeLong, Cynthia, Bales, Kelly, Merchant, Kalpana M.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

8

LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits

Baptista, Marco A. S., Merchant, Kalpana, Barrett, Ted, Bhargava, Sakshi, Bryce, Dianne K., Ellis, J. Michael, Estrada, Anthony A., Fell, Matthew J., Fiske, Brian K., Fuji, Reina N., Galatsis, Paul, H

Journal:

Science Translational Medicine

Year:

2020

File:

PDF, 3.30 MB

2020

9

Longitudinal Measurements of Glucocerebrosidase activity in Parkinsonâs patients

Alcalay, Roy N., Wolf, Pavlina, Chiang, Ming Sum Ruby, Helesicova, Karolina, Zhang, Xiaokui Kate, Merchant, Kalpana, Hutten, Samantha J., Scherzer, Clemens, CaspellâGarcia, Chelsea, Blauwendraat, Co

Journal:

Annals of Clinical and Translational Neurology

Year:

2020

File:

PDF, 2.49 MB

2020

10

Induction of c-fos mRNA in Rat Medial Prefrontal Cortex by Antipsychotic Drugs: Role of Dopamine D2 and D3 Receptors

Merchant, Kalpana M., Figur, Lana M., Evans, Dawna L.

Journal:

Cerebral Cortex

Year:

1996

Language:

english

File:

PDF, 7.56 MB

english, 1996

11

Detection of age-dependent brain injury in a mouse model of brain amyloidosis associated with Alzheimer's disease using magnetic resonance diffusion tensor imaging

Shu-Wei Sun, Sheng-Kwei Song, Michael P. Harms, Shiow-Jiuan Lin, David M. Holtzman, Kalpana M. Merchant, John J. Kotyk

Journal:

Experimental Neurology

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

12

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders

Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M.

Journal:

Frontiers in Pharmacology

Year:

2014

Language:

english

File:

PDF, 978 KB

english, 2014

13

Differential distribution of γ-aminobutyric acidA, receptor subunit (α1, α2, α3, α5 and β2+3) immunoreactivity in the medial prefrontal cortex of the rat

Edwige Dunn, Jean-Marc Fritschy, Donald B. Carter, Kalpana M. Merchant

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 642 KB

english, 1996

14

Effect of muscimol on haloperidol-induced alteration of neurotensin gene expression in the striatum and nucleus accumbens in the rat

Kathleen P. Decker, Peter P. Roy-Byrne, Kalpana M. Merchant

Journal:

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

15

Novel high-sensitivity ELISAs for alpha-synuclein quantification in multiple matrices, including human CSF and plasma

Li, Linglin, Liu, Feng, Ryder, John, Merchant, Kalpana, DeMattos, Ronald

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 77 KB

english, 2012

16

Increased brain bio-distribution and chemical stability and decreased immunogenicity of an engineered variant of GDNF

Smith, Rosamund C., O'Bryan, Linda M., Mitchell, Pamela J., Leung, Donmienne, Ghanem, Mahmoud, Wilson, Jonathan M., Hanson, Jeff C., Sossick, Sandra, Cooper, Jane, Huang, Lihua, Merchant, Kalpana M.,

Journal:

Experimental Neurology

Year:

2015

Language:

english

File:

PDF, 1006 KB

english, 2015

17

Phosphodiesterase 10A inhibitor, MP-10 (PF-2545920), produces greater induction of c-Fos in dopamine D2 neurons than in D1 neurons in the neostriatum

Wilson, Jonathan M., Ogden, Ann Marie L., Loomis, Sally, Gilmour, Gary, Baucum, Anthony J., Belecky-Adams, Teri L., Merchant, Kalpana M.

Journal:

Neuropharmacology

Year:

2015

Language:

english

File:

PDF, 2.09 MB

english, 2015

18

Coexpression of neurotensin and c-fos mRNAs in rat neostriatal neurons following acute haloperidol

Merchant, Kalpana M., Miller, Margaret A.

Journal:

Molecular Brain Research

Year:

1994

Language:

english

File:

PDF, 999 KB

english, 1994

19

Methamphetamine-induced changes in the striatal-nigral dynorphin system: role of D-1 and D-2 receptors

Glen R. Hanson, Kalpana M. Merchant, Anita A. Letter, Lloyd Bush, James W. Gibb

Journal:

European Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 155 KB

english, 1987

20

Genome-wide association of longitudinal volumetric mri measurements in the Alzheimer's Disease Neuroimaging Initiative (ADNI) study

Jia Sun, Laura Nisenbaum, Robert Dean, Mark Farmen, Kalpana Merchant, Michael Hutton, Peng Yu

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

21

Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: a placebo-controlled trial

Mark H Corrigan, Christopher C Gallen, M.Luisa Bonura, Kalpana M Merchant

Journal:

Biological Psychiatry

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

22

FREE FEEDING OF SCHOOL CHILDREN AT MARSEILLES.

Merchant, Kalpana M., Miller, Margaret A.

Journal:

Year:

1907

Language:

english

File:

PDF, 622 KB

english, 1907

23

Analysis of physiological α-synuclein by non-denaturing gel electrophoresis

Liu, Feng, Li, Linglin, Ryder, John, Hole, Justin, Racke, Margaret, Merchant, Kalpana, DeMattos, Ronald

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 52 KB

english, 2012

24

Differential Induction of Neurotensin and c-fos Gene Expression by Typical Versus Atypical Antipsychotics

Kalpana M. Merchant and Daniel M. Dorsa

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.29 MB

english, 1993

25

Dopamine D2 receptors exert tonic regulation over discrete neurotensin systems of the rat brain

Kalpana M. Merchant, Lloyd G. Bush, James W. Gibb, Glen R. Hanson

Journal:

Year:

1989

Language:

english

File:

PDF, 711 KB

english, 1989

26

Differential Loss of Presynaptic Dopaminergic Markers in Parkinsonian Monkeys

Stephenson, Diane T., Childs, Mary Abigail, Li, Qiu, Carvajal-Gonzalez, Santos, Opsahl, Alan, Tengowski, Mark, Meglasson, Martin D., Merchant, Kalpana, Emborg, Marina E.

Journal:

Cell Transplantation

Year:

2007

Language:

english

File:

PDF, 541 KB

english, 2007

27

209 - Blockade of the expression of behavioral sensitization to amphetamine by the selective dopamine D4 receptor antagonist, PNU-101387G

Lana M. Needham, Kalpana M. Merchant

Journal:

Schizophrenia Research

Year:

1997

Language:

english

File:

PDF, 113 KB

english, 1997

28

EEDQ Reduces the Striatal Neurotensin mRNA Response to Haloperidol

Monique R Adams, Dorcas J Dobie, Kalpana M Merchant, Alan Unis, Daniel M Dorsa

Journal:

Year:

1997

Language:

english

File:

PDF, 423 KB

english, 1997

29

Effects of amphetamine analogs on neurotensin concentrations in rat brain

Kalpana M. Merchant, Anita A. Letter, Michel Johnson, Donna M. Stone, James W. Gibb, Glen R. Hanson

Journal:

European Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 330 KB

english, 1987

30

The role of NMDA receptor systems in neuropeptide responses to stimulants of abuse

Hanson, Glen R., Singh, Nanda, Merchant, Kalpana, Johnson, Michel, Gibb, James W.

Journal:

Drug and Alcohol Dependence

Year:

1995

Language:

english

File:

PDF, 375 KB

english, 1995

31

Haloperidol rapidly increases the number of neurotensin mRNA-expressing neurons in neostriatum of the rat brain

Kalpana Mahesh Merchant, Margaret A. Miller, E. Alexandra Ashleigh, Daniel M. Dorsa

Journal:

Year:

1991

Language:

english

File:

PDF, 1.97 MB

english, 1991

32

Characterization of methamphetamine effects on the striatal-nigral dynorphin system

Glen R. Hanson, Kalpana M. Merchant, Anita A. Letter, Lloyd Bush, James W. Gibb

Journal:

European Journal of Pharmacology

Year:

1988

Language:

english

File:

PDF, 650 KB

english, 1988

33

Genome-wide association of longitudinal volumetric MRI measurements in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study

Jia Sun, Laura Nisenbaum, Robert Dean, Mark Farmen, Kalpana Merchant, Michael Hutton, Peng Yu

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

34

Differential loss of dopamine D2 receptor mRNA isoforms during aging in Fischer-344 rats

Merchant, Kalpana M., Dobie, Dorcas J., Dorsa, Daniel M.

Journal:

Neuroscience Letters

Year:

1993

Language:

english

File:

PDF, 568 KB

english, 1993

35

Role of dopamine D-1 and D-2 receptors in the regulation of neurotensin systems of the neostriatum and the nucleus accumbens

Kalpana M. Merchant, J.W. Gibb, G.R. Hanson

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 286 KB

english, 1989

36

Expression of the Proneurotensin Gene in the Rat Brain and Its Regulation by Antipsychotic Drugs

KALPANA M. MERCHANT, DORCAS J. DOBIE, DANIEL M. DORSA

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 2.20 MB

english, 1992

37

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

Dage, Jeffrey L., Colvin, Ellen M., Fouillet, Antoine, Langron, Emily, Roell, William C., Li, Jingling, Mathur, Sachin X., Mogg, Adrian J., Schmitt, Matthew G., Felder, Christian C., Merchant, Kalpana

Journal:

Psychopharmacology

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

38

The Selective Dopamine D4 Receptor Antagonist, PNU-101387G, Prevents Stress-Induced Cognitive Deficits in Monkeys

Amy F.T Arnsten, Beth Murphy, Kalpana Merchant

Journal:

Neuropsychopharmacology

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

39

The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites

Elisa Greggio, Jean-Marc Taymans, Eugene Yuejun Zhen, John Ryder, Renée Vancraenenbroeck, Alexandra Beilina, Peng Sun, Junpeng Deng, Howard Jaffe, Veerle Baekelandt, Kalpana Merchant, Mark R. Cookson

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 383 KB

english, 2009

40

Comparison of responses by striatonigral substance P and neurokinin A systems to methamphetamine treatment

Hanson, Glen R., Letter, Anita A., Merchant, Kalpana, Gibb, James W.

Journal:

Year:

1986

Language:

english

File:

PDF, 561 KB

english, 1986

41

Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree

Kim, Kwi Hye, Liu, Jiangang, Sells Galvin, Rachelle J., Dage, Jeffrey L., Egeland, Janice A., Smith, Rosamund C., Merchant, Kalpana M., Paul, Steven M., Zheng, Deyou

Journal:

Year:

2015

Language:

english

File:

PDF, 1.63 MB

english, 2015

42

Distinct 5-HT1B and 5-HT1D serotonin receptors in rat: Structural and pharmacological comparison of the two cloned receptors

Hamblin, Mark W., McGuffin, Robert W., Metcalf, Mark A., Dorsa, Daniel M., Merchant, Kalpana M.

Journal:

Molecular and Cellular Neuroscience

Year:

1992

Language:

english

File:

PDF, 1.71 MB

english, 1992

43

Expression of GAD65 and GAD67 immunoreactivity in MPTP-treated monkeys with or without l-DOPA administration

Diane T. Stephenson, Qiu Li, Carol Simmons, Mark A. Connell, Martin D. Meglasson, Kalpana Merchant, Marina E. Emborg

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 886 KB

english, 2005

44

BMY 14802, a potential antipsychotic drug, increases expression of proneurotensin mRNA in the rat striatum

Levant, Beth, Merchant, Kalpana M., Dorsa, Daniel M., Nemeroff, Charles B.

Journal:

Molecular Brain Research

Year:

1992

Language:

english

File:

PDF, 1.61 MB

english, 1992

45

P3-324 Further evidence of deficits in hippocampal synaptic viability in young, pre-plaque PDAPP mice

Sahr, Robert N., Ryder, John W., Koger, Deanna, Bales, Kelly R., Merchant, Kalpana M.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

46

Increased Levels of Proneurotensin/Neuromedin N mRNA in Rat Striatum and Nucleus Accumbens Induced by 7-OH-DPAT and Nafadotride

Beth Levant, Bina Garimelli, Rose A Shafer, Kalpana M Merchant

Journal:

Neuropsychopharmacology

Year:

1999

Language:

english

File:

PDF, 1.74 MB

english, 1999

47

Changes in the limbic neurotensin systems induced by dopaminergic drugs

Kalpana M. Merchant, A.A. Letter, J.W. Gibb, G.R. Hanson

Journal:

European Journal of Pharmacology

Year:

1988

Language:

english

File:

PDF, 656 KB

english, 1988

48

Neurotensin mRNA Expression in Response to Haloperidol Is Decreased in the Dorsolateral Striatum of Aged Rats

DORCAS J. DOBIE, KALPANA M. MERCHANT, MURRAY A. RASKIND, DANIEL M. DORSA

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 290 KB

english, 1992

49

Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: Expression in areas associated with learning and memory

Xia, Zhengui, Refsdal, Cheryl D., Merchant, Kalpana M., Dorsa, Daniel M., Storm, Daniel R.

Journal:

Year:

1991

Language:

english

File:

PDF, 10.97 MB

english, 1991

50

LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients

Ysselstein, Daniel, Nguyen, Maria, Young, Tiffany J., Severino, Alex, Schwake, Michael, Merchant, Kalpana, Krainc, Dimitri

Journal:

Nature Communications

Year:

2019

File:

PDF, 1.08 MB

2019

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